abstract
Investigating the effectiveness of three antifungal fabrics on the
growth of Trichophyton equinum and Microsporum canis
in-vitro. (E. Wiggens, F. Ruedisueli)
Ringworm is
a fungal infection that parasitises keratinised epidermal structures
such as outer stratum corneum of the skin, hair, feathers, nails,
claws, and hooves. The most common cause of ringworm in equines
is caused by Trichophyton equinum, and it is a worldwide problem.
Microsporum canis is the most common cause of ringworm in cats and
dogs. Classical signs of infection include lesions on the skin and
hair loss. Topical and systemic treatments help the infection to
resolve quicker and reduce environmental contamination. Newer treatments
include fungal vaccines that can reduce the severity of infection
in large groups of animals, and help in reducing the spread of infection.
The potential for an alternative preventative approach is investigated
here.
The antifungal
effectiveness of Tolnaftate incorporated into three fabrics at different
inclusion levels was investigated against Trichophyton equinum and
Microsporum canis in-vitro. Fabrics contained high, medium or low
levels of Tolnaftate. All three fabrics were tested untreated (no
washing). The fabric containing high levels of Tolnaftate was also
tested after being washed with detergent at 40° C and 90°
C. Measurements were made of the surface areas of the inhibition
zones, and of the inhibition rings.
The results
demonstrate that medium and high levels of Tolnaftate incorporated
into acrylic fibre inhibited the growth of T. equinum and M. canis.
It was also shown that washing with detergent at 40° C and 90°
C, had no effect on the antifungal properties of the fabric containing
high levels of Tolnaftate. These results show a potential for an
alternative approach in preventing ringworm infections in companion
animals.
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